PubMed日本語 - 屋内空気汚染と中国の女性の非喫煙者の間の肺癌のリスク。―QLifePro医療翻訳医療翻訳 QLifePro



Indoor air pollution and risk of lung cancer among Chinese female non-smokers.

Published date 2013 Jan 12

Indoor air pollution and risk of lung cancer among Chinese female non-smokers.


Published date



Lina Mu, Li Liu, Rungui Niu, Baoxing Zhao, Jianping Shi, Yanli Li, Mya Swanson, William Scheider, Jia Su, Shen-Chih Chang, Shunzhang Yu, Zuo-Feng Zhang


Department of Social and Preventive Medicine, School of Public Health and Health Professions, University at Buffalo, SUNY, 270 Farber Hall, Buffalo, NY 14214, USA.


PURPOSE: To investigate indoor particulate matter (PM) level and various indoor air pollution exposure, and to examine their relationships with risk of lung cancer in an urban Chinese population, with a focus on non-smoking women.


METHODS: We conducted a case-control study in Taiyuan, China, consisting of 399 lung cancer cases and 466 controls, of which 164 cases and 218 controls were female non-smokers. Indoor PM concentrations, including PM(1), PM(2.5), PM(7), PM(10), and TSP, were measured using a particle mass monitor. Unconditional logistic regression models were used to calculate odds ratios (ORs) and 95 % confidence intervals after adjusting for age, education, annual income, and smoking.


RESULTS: Among non-smoking women, lung cancer was strongly associated with multiple sources of indoor air pollution 10 years ago, including heavy exposure to environmental tobacco smoke at work (aOR = 3.65), high frequency of cooking (aOR = 3.30), and solid fuel usage for cooking (aOR = 4.08) and heating (aOR(coal stove) = 2.00). Housing characteristics related to poor ventilation, including single-story, less window area, no separate kitchen, no ventilator, and rarely having windows open, are associated with lung cancer. Indoor medium PM(2.5) concentration was 68 μg/m(3), and PM(10) was 230 μg/m(3). PM levels in winter are strongly correlated with solid fuel usage for cooking, heating, and ventilators. PM(1) levels in cases are more than 3 times higher than that in controls. Every 10 μg/m(3) increase in PM(1) is associated with 45 % increased risk of lung cancer.


CONCLUSIONS: Indoor air pollution plays an important role in the development of lung cancer among non-smoking Chinese women.



屋内のPM濃度は、粒子腫瘤監視装置を使用して、PM(1)、PM (2.5)、PM(7)、Pm(10)とTSPを含んで、測定された。

結果タバコを吸わない女性の間で、肺癌は仕事の(aOR = 3.65)副流煙、料理(aOR = 3.30)の高周波と料理(aOR = 4.08)と加熱(aOR(石炭ストーブ)= 2.00)のための固体燃料使用への重い露出を含む10年前、屋内空気汚染の複数のもとと強く関係していた。
屋内の中間のPM (2.5)濃度は68μg/m(3)であった、そして、PM(10)は230μg/m(3)であった。


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